White Paper Video Surveillance

White paper video surveillance for rapid and inexpensive chemical processes in the new white paper by METTLER TOLEDO four case studies will be presented, where the in-situ monitoring researchers qualitative reaction information provided, which cannot be identified with offline method of sampling. This in-depth information led to a faster optimization, higher yields and increased security, which can bring in turn considerable cost savings. METTLER TOLEDO presented a new contribution to the informative white paper series recent advances in organic chemistry. This free white paper titled “In-situ monitoring chemical reactions – a molecular video” shows four recent case studies where cutting-edge inline monitoring techniques yielded useful insights into chemical reactions. This information allowed researchers for the accurate characterization of reactions, process optimization and faster results and contributed essentially to the fact that they “more with less reach”could – a motto that runs like a thread through the competitive chemical development laboratory. The presented case studies show how the inline monitoring technologies in the middle infrared range (mid-IR) differs from offline-Probenahmenverfahren like the Hochleistungsflussigkeitschromatografie (HPLC).

Each study includes a specific type of experiment, including the successful use of a bimetallic catalyst and the one-step oxidative cleavage, and shows that the advanced in-situ spectroscopy and accordingly provided molecular video can offer crucial insights into complex reaction mechanisms, rate and pathways. This allows a fast characterization of the various reaction types and thus a timely optimization, improved batch consistency and increased operator safety, especially in experiments under high pressure or at high temperatures. More proven benefits of inline monitoring, represented by METTLER TOLEDO ReactIR tested examples included the possible monitoring of bubbles and solid matter, which enabled a well-founded information collection during a complex catalytic hydrogenation. The sensitivity of the absorption bands compared with water also promoted the proper characterization in aqueous environments. Finally, the possibility to characterize reactions without a sampling allowed observation of chemistry in their natural environment, the maintenance of concentrations of reaction partners, avoiding phenomena such as deletions, and the collection of qualitative and quantitative data depending on the objective of the experiment. These and other advantages around the world contribute to an increased usage of the in-situ monitoring in science and production laboratories. Download this whitepaper for free, and get a profound insight into the representative attempts and learn how the in-situ monitoring allows a more cost-efficient academic research and production: de.mt.com/de/de/home/supportive_content/White_Papers/… About Mettler Toledo: METTLER TOLEDO specializes in precision instruments for professional use.

In addition to many other applications in the pharmaceutical and chemical industry, food industry and cosmetics, laboratory instruments, METTLER Toledo come in scientific research, the search for new pharmaceuticals and laboratories of quality control to the application. Many of these customers, the extensive industrial solutions from METTLER TOLEDO in addition to laboratory facilities cover the various stages of the production process. The solutions offered range from acceptance of raw materials of different manufacturing processes and in-line process control, packaging inspection at the end of the line to logistics and shipping. More and more, customers fully integrate these solutions in your production environment, where they contribute to the automation of work processes.